Work with biological hazards at UNC is documented on Schedule F: Biological Hazards Registration of the online Laboratory Safety Plan. Because laboratory practices, facilities, and safety equipment for work at or above Biosafety Level 2 is regulated at federal, state, and local levels, this chapter will cover some basic information about biological hazards, including the use of established human cell lines and those found in human blood and other potentially infectious materials (OPIM). For more information on this topic, consult the UNC Biological Safety Manual.