Laboratories working with highly toxic chemicals and/or select carcinogens must include standard operating procedures in the Laboratory Safety Plan (LSP) describing the hazards of the compounds, safety precautions and emergency procedures in the event of a spill. Refer to Chapter 2 for instructions on completing an LSP. In addition to the safety practices described for use of toxic materials, several other special safety precautions are necessary for highly toxic chemicals and select carcinogens.