Skip Navigation
Increase font size
Decrease font size

Biological Safety Manual

Download entire manual. This section has been reviewed and updated as needed: May 2015.


Chapter 1: Introduction

Chapter 2: Biological Risk Assessment

Chapter 3: Principles Of Biosafety

Chapter 4: Laboratory Biosafety Level Criteria

Chapter 5: Vertebrate Animal Biosafety Level Criteria for Vivarium Research Facilities

Chapter 6: Principles of Laboratory Biosecurity

Chapter 7: Occupation Health and Immunoprophylaxis

Chapter 8: Agent Summary Statements

Chapter 9: Primary Containment for Biohazards: Selection, Installation and Use of Biological Safety Cabinets

Chapter 10: Decontamination and Disinfection

Chapter 11: Transportation of Infectious Substances

Chapter 12: Agricultural Pathogen Biosafety

The contents of this chapter were provided by USDA. All questions regarding its contents should be forwarded to the USDA.

Chapter 13: Arthropod Containment Guidelines (ACG)

Chapter 14: Select Agents and Toxins

Chapter 15: Integrated Pest Management (IPM)

Chapter 16: Working With Human, NHP and Other Mammalian Cells and Tissues

Chapter 17: Guidelines for Work With Toxins of Biological Origin

Chapter 18: NIH Oversight of Research Involving Recombinant Biosafety Issues

Chapter 19: Resources for Information