Biological Safety Manual
The University of North Carolina at Chapel Hill
Environment, Health and Safety Office
Environment, Health and Safety Office
Download entire manual or pick and choose chapters below.
Table of Contents
- Foreword
- Chapter 1: Introduction
- Chapter 2: Biological Risk Assessment
- Chapter 3: Principles of Biosafety
- Chapter 4: Laboratory Biosafety Level Criteria
- Section I: Designating Biological Safety Level 2 at UNC
- Appendix A: Biological Safety Level 2 Checklist
- Chapter 5: Vertebrate Animal Biosafety Level Criteria for Vivarium Research Facilities
- Chapter 6: Principles of Laboratory Biosecurity
- Chapter 7: Occupation Health and Immunoprophylaxis
- Chapter 8: Agent Summary Statements
- Section I: Bacterial Agents
- Section II: Fungal Agents
- Section III: Parasitic Agents
- Section IV: Rickettsial Agents
- Section V: Viral Agents
- Section VI: Arboviruses and Related Zoonotic Viruses
- Section VII: Toxin Agents
- Section VIII: Prion Diseases
- Chapter 9: Primary Containment for Biohazards: Selection, Installation and Use of Biological Safety Cabinets
- Chapter 10: Decontamination and Disinfection
- Section I: Biological Waste Disposal Policy
- Chapter 11: Transportation of Infectious Substances
- Chapter 12: Agricultural Pathogen Biosafety
- Chapter 13: Arthropod Containment Guidelines (ACG)
- Chapter 14: Select Agents and Toxins
- Chapter 15: Integrated Pest Management (IPM)
- Chapter 16: Working with Human, NHP and Other Mammalian Cells and Tissues
- Section I: Exposure Control Plan
- Chapter 17: Guidelines for Work with Toxins of Biological Origin
- Chapter 18: NIH Oversight of Research Involving Recombinant Biosafety Issues
- Chapter 19: Resources for Information
- Index: Acronyms

